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Preventing recurrence in Sonic Hedgehog Subgroup Medulloblastoma using OLIG2 inhibitor CT-179
Yuchen Li, Chaemin Lim, Taylor Dismuke et al.
09 June 2023, PREPRINT (Version 1) available at Research Square
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Biological functions of the Olig gene family in brain cancer and therapeutic targeting
Szu JI, Tsigelny IF, Wojcinski A, Kesari S.
Front Neurosci. 2023 May 18;17:1129434.
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OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma
Zhenhua XuNajiba MuradDaniel MalawskyRan TaoSamuel Rivero-HinojosaDörthe HoldhofUlrich SchüllerPeng ZhangChristopher LazarskiBrian R. RoodRoger PackerTimothy GershonYanxin Pei;
Clin Cancer Res 1 October 2022; 28 (19): 4278–4291.
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Novel Small Molecule Inhibitors Of The OLIG2 Transcription Factor: Promising New Therapeutics For Glioblastoma
Alton, G., & Kesari, S.
Future Oncology (London, England), 2016:12(8), 1001–4.
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Multiple Spatially Related Pharmacophores Define Small Molecule Inhibitors of OLIG2 in Glioblastoma
Tsigelny, I. F., Mukthavaram, R., Kouznetsova, V. L., Chao, Y., Babic, I., Nurmemmedov, E., … Kesari, S. (2015).
Oncotarget, Oct 30(Online). doi:10.18632/oncotarget.5633
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Antagonistic Modulation of Gliomagenesis by Pax6 And OLIG2 in PDGF-Induced Oligodendroglioma
Appolloni I, Calzolari F, Barilari M, Terrile M, Daga A, Malatesta P.
International Journal Of Cancer (Journal International du Cancer). 2012;131(7):E1078–87.
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The Central Nervous System-Restricted Transcription Factor OLIG2 Opposes P53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma
Mehta S, Huillard E, Kesari S, Maire CL, Golebiowski D, Harrington EP, Alberta J a, Kane MF, Theisen M, Ligon KL, Rowitch DH, Stiles CD.
Cancer cell. 2011;19(3):359–71.
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Malignant Gliomas in Adults
Wen PY, Kesari S.
The New England journal of medicine. 2008;359(5):492–507.
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OLIG2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta J a, Bachoo RM, Kane M, Louis DN, Depinho R a, Anderson DJ, Stiles CD, Rowitch DH.
Neuron. 2007;53(4):503–17.
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The Oligodendroglial Lineage Marker OLIG2 is Universally Expressed in Diffuse Gliomas
Ligon KL, Alberta J a, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH.
Journal of neuropathology and experimental neurology. 2004;63(5):499–509.